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849b: De-novo Freestyle 34: Hand-folding Round

Closed since over 8 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
February 25, 2014
Expires
Max points
100
Description

This is a corrected repost of Puzzle 849a. We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

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Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Alanines at residues 9 and 74 are highly predicted to be part of a sheet. However, the Alanines at residues 57-59 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.

alcor29 Lv 1

Can you please allow us to go reload the work done on 849 to 849b? Not a good thing to waste a couple of hours just to throw it away. Thanks.