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837: 65 Residue Monomer Design

Closed since over 8 years ago

Intermediate Overall Design

Summary


Created
January 27, 2014
Expires
Max points
100
Description

This is a single-chain design puzzle with 65 residues. This puzzle is very similar to Puzzle 817, and will help us benchmark the recent Foldit update. There are 3 filters enabled on this puzzle: the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well; the Core Existence filter checks that at least 30% of the residues are buried in the core of your design; and the Fragment Filter scans for parts of your design that are unlikely to fold up naturally. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!

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