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823: Large CASP ROLL Target R0044

Closed since almost 9 years ago

Intermediate Overall Prediction CASP ROLL

Summary


Created
December 15, 2013
Expires
Max points
100
Description

This unsolved CASP ROLL target is larger than most Foldit puzzles, at 204 residues. There are no homologs, so we are starting you from an extended chain. After this puzzle closes, there will be one more round with server predictions. See the puzzle comments for secondary structure predictions.

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Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Glutamates at residues 27 & 28 are predicted to be in a helix. However, the Glutamates at residues 159 & 161 are predicted to be part of a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.

bkoep Staff Lv 1

When Puzzle 823 closes, we'll post a follow-up puzzle for this CASP ROLL target with server predictions. We can extend the deadline for the follow-up puzzle if you would like.