Placeholder image of a protein
Icon representing a puzzle

400: De-novo Freestyle 4

Closed since over 11 years ago

Advanced Overall Prediction

Summary


Created
February 15, 2011
Expires
Max points
100
Description

Our 400th puzzle is another currently unsolved protein that we are giving to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, you'll notice this sequence is similar to Puzzle 398: De-novo Freestyle 3. THIS PUZZLE HAS BEEN EXTENDED BY 1 DAY!

Top groups


  1. Avatar for Anthropic Dreams 100 pts. 11,964
  2. Avatar for Contenders 2. Contenders 84 pts. 11,917
  3. Avatar for Go Science 3. Go Science 70 pts. 11,706
  4. Avatar for Pauling's Pitbulls 4. Pauling's Pitbulls 58 pts. 11,677
  5. Avatar for Natural Abilities 5. Natural Abilities 48 pts. 11,494
  6. Avatar for L'Alliance Francophone 6. L'Alliance Francophone 39 pts. 11,246
  7. Avatar for Void Crushers 7. Void Crushers 32 pts. 11,183
  8. Avatar for Slovak National Team 8. Slovak National Team 26 pts. 11,163
  9. Avatar for foldeRNA 9. foldeRNA 20 pts. 11,153
  10. Avatar for Deleted group 10. Deleted group pts. 11,083

  1. Avatar for aap
    1. aap Lv 1
    100 pts. 12,003
  2. Avatar for Mark- 2. Mark- Lv 1 99 pts. 11,915
  3. Avatar for keypad5 3. keypad5 Lv 1 98 pts. 11,913
  4. Avatar for grabhorn 5. grabhorn Lv 1 95 pts. 11,816
  5. Avatar for groovermctuber 6. groovermctuber Lv 1 94 pts. 11,677
  6. Avatar for infjamc 7. infjamc Lv 1 92 pts. 11,592
  7. Avatar for drjr 8. drjr Lv 1 91 pts. 11,565
  8. Avatar for BootsMcGraw 9. BootsMcGraw Lv 1 90 pts. 11,502
  9. Avatar for Mr_Jolty 10. Mr_Jolty Lv 1 89 pts. 11,494

Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 26 is highly predicted to be part of a helix. However, the Leucine at residue 34 is predicted to have an equal probability of being anything.

mikedressner Lv 1

The protein is Bile acid 7a-dehydratase

It belongs to the bacteria organism Eubacterium sp.

Catalyzes the dehydratation of 7-alpha,12-alpha-dihydroxy-3-oxochol-4-enoate. The enzyme can also use 7-alpha-hydroxy-3-oxochol-4-enoate as a substrate but not 7-alpha,12-alpha-dihydroxy-3-oxochol-5-beta-anoate, 3-alpha,7-alpha,12-alpha-trihydroxychol-5-beta-anoate or 7-beta-hydroxy-3-oxochol-4-enoate

For more info: Go to the uniprot ascession number P19412