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366: Back Me Up 1

Closed since about 12 years ago

Intermediate

Summary


Created
September 27, 2010
Expires
Max points
100
Description

We designed a helix to contact our substrate, but the helix needs back up to stay in place. The goal of this puzzle is to design a loop and mutate residues to create a more stable configuration, making a more active catalyst (ie create a Helix-Loop-Helix). See the blogpost for more details: http://fold.it/portal/node/988587

Top groups


  1. Avatar for Contenders 100 pts. 14,280
  2. Avatar for Void Crushers 2. Void Crushers 81 pts. 14,276
  3. Avatar for Russian team 3. Russian team 65 pts. 14,253
  4. Avatar for Anthropic Dreams 5. Anthropic Dreams 41 pts. 14,225
  5. Avatar for Deleted group 6. Deleted group pts. 14,199
  6. Avatar for Natural Abilities 7. Natural Abilities 24 pts. 14,177
  7. Avatar for SETI.Germany 8. SETI.Germany 18 pts. 14,145
  8. Avatar for Deleted group 9. Deleted group pts. 14,140
  9. Avatar for Mojo Risin' 10. Mojo Risin' 10 pts. 14,110

  1. Avatar for Mark-
    1. Mark- Lv 1
    100 pts. 14,278
  2. Avatar for TheGUmmer 2. TheGUmmer Lv 1 99 pts. 14,274
  3. Avatar for mat747 3. mat747 Lv 1 97 pts. 14,246
  4. Avatar for BitSpawn 5. BitSpawn Lv 1 94 pts. 14,233
  5. Avatar for keypad5 6. keypad5 Lv 1 92 pts. 14,232
  6. Avatar for Deleted player 7. Deleted player pts. 14,224
  7. Avatar for John McLeod 8. John McLeod Lv 1 89 pts. 14,221
  8. Avatar for infjamc 9. infjamc Lv 1 87 pts. 14,219
  9. Avatar for g_b 10. g_b Lv 1 86 pts. 14,216

Comments


beta_helix Staff Lv 1

We do not want you to change Alanine 54 or Glycine 55, however you are free to move the backbone there in order to make the helix move into a better position.

You cannot delete any residues, but you may add 0-5 residues anywhere between residues 44-54.