Placeholder image of a protein
Icon representing a puzzle

1211: 85 Residue Monomer Design: Rama Map

Closed since over 6 years ago

Intermediate Overall Design

Summary


Created
March 25, 2016
Expires
Max points
100
Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups


  1. Avatar for Contenders 100 pts. 10,672
  2. Avatar for Go Science 2. Go Science 79 pts. 10,658
  3. Avatar for Beta Folders 3. Beta Folders 61 pts. 10,647
  4. Avatar for Anthropic Dreams 4. Anthropic Dreams 47 pts. 10,647
  5. Avatar for L'Alliance Francophone 5. L'Alliance Francophone 35 pts. 10,558
  6. Avatar for Gargleblasters 6. Gargleblasters 26 pts. 10,554
  7. Avatar for Void Crushers 7. Void Crushers 19 pts. 10,493
  8. Avatar for Hun-Magyar Csapat 8. Hun-Magyar Csapat 14 pts. 10,398
  9. Avatar for Deleted group 9. Deleted group pts. 10,337
  10. Avatar for Italiani Al Lavoro 10. Italiani Al Lavoro 7 pts. 10,153

  1. Avatar for Mark-
    1. Mark- Lv 1
    100 pts. 10,663
  2. Avatar for Scopper 2. Scopper Lv 1 98 pts. 10,658
  3. Avatar for pauldunn 3. pauldunn Lv 1 96 pts. 10,649
  4. Avatar for MurloW 4. MurloW Lv 1 93 pts. 10,647
  5. Avatar for Deleted player 5. Deleted player pts. 10,642
  6. Avatar for gmn 6. gmn Lv 1 89 pts. 10,629
  7. Avatar for LociOiling 7. LociOiling Lv 1 87 pts. 10,599
  8. Avatar for johnmitch 8. johnmitch Lv 1 84 pts. 10,597
  9. Avatar for mirp 9. mirp Lv 1 82 pts. 10,585
  10. Avatar for retiredmichael 10. retiredmichael Lv 1 80 pts. 10,576

Comments


bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.