Puzzle 1431 Unsolved De-novo Freestyle 117 Deadline Extended

Puzzle 1431 Unsolved De-novo Freestyle 117 has been extended by two weeks! After discussion with the community and Foldit admin team, we agree that a week for such a big puzzle was too limiting. We're hoping all find the two additional weeks useful for full exploration of the puzzle and apologize that the extension came so close to the actual deadline.

(Mon, 09/25/2017 - 22:03  |  1 comment)

We're Hiring.... You Looking?

Seth Cooper's (scooper) team at Northeastern University is hiring a part-time game developer to work on Foldit! This is an on-campus position, so those who apply will need to be local to Boston. Minimum qualifications include:

- Bachelor’s Degree
- C++ development
- Minimum of 2 – 5 years of experience required. Interest in biochemistry is preferred.
- Version control (preferably git)
- Experience with large codebases
- Works well in teams and independently
- Self-motivated with great organization, communication, and problem-solving skills

(Thu, 09/21/2017 - 20:12  |  0 comments)

Updates from the Foldit Team

Here are some things the Foldit team has been working on lately:

  • bkoep has been purifying proteins in the lab. Below is a picture of crystals of a Foldit player-designed protein. He harvested a few of these yesterday, and will try x-ray diffraction in the next couple of weeks.
  • Protein Crystal

  • scooper has finished with his study of the Foldit touch interface. Results are currently being reviewed.
(Wed, 09/20/2017 - 20:45  |  4 comments)

New Puzzle Type: Small Molecule Design!

Hi everyone, today we're officially launching the small molecule design (drug design) mode of Foldit, with Puzzle 1432: HIV Protease Inhibitor Small Molecule Design!
See the latest blog post for more information. We appreciate any feedback you have regarding this new puzzle type!

(Tue, 09/19/2017 - 23:29  |  1 comment)

New Release!

Hey everyone,

We've just pushed a small update out for the client with some fixes to Drug Design and Ligand-based puzzles.

Drug Design:
* Various fixes to the drug design code, including ensuring that these tools are properly disabled on non-drug design puzzles.

As always, thanks to our devprev users for helping test this release!

(Tue, 09/19/2017 - 20:19  |  1 comment)

Developer Preview Release Soon

Hey everyone, we have a small update coming out soon with some features and fixes. Here's the full list:

Intro Puzzles:
* Added a series of intro puzzles for the Blueprint Tool and Conditions.

Drug Design:
* Various fixes to the drug design code, including ensuring that these tools are properly disabled on non-drug design puzzles.

(Wed, 09/13/2017 - 23:15  |  1 comment)

San Francisco

We are also looking for Foldit players who will be in San Francisco around mid-October. If you will be in the area and would like to find out more, please send a PM to Seth Cooper.

(Wed, 09/13/2017 - 14:20  |  0 comments)

New Category: Experimental!

Hey everyone,

We've just created a new puzzle category - the Experimental category.

We're trying out this category as a way to introduce new puzzle types that aren't necessarily fit for prime time quite yet. If a puzzle is out of devprev testing, but we're still in a state of heavy refinement, we've added the Experimental category to keep it segregated from the normal puzzles.

This is useful because, if there are issues with the puzzle, they wont affect your Overall or other category scores. It also gives credit to players who are adapting to the new rulesets the fastest!

(Fri, 09/08/2017 - 20:34  |  3 comments)

New Paper out of the Baker Lab

Recently, a group from the Baker lab published a paper in Science describing a high-throughput way to test lots of protein designs at once. That paper is now available, but only though a specific link on the Baker lab website. To view the paper, head to the Baker lab site and click on second item listed (Global analysis of protein folding using massively parallel design, synthesis, and testing).

(Fri, 09/01/2017 - 21:53  |  2 comments)

Puzzle 1420 Deadline Extended

Due to recent instabilities in the scoring system, the expiration date of Puzzle 1420 has been pushed back 24 hours, to August 30 at 23:00 UTC. We expect the current scoreboard issues to be resolved later today.

(Tue, 08/29/2017 - 20:18  |  3 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons