puzzle picture
968: Final CASP11 Target Ts812: Sparse Data Contacts
Status: Closed

Summary

Name: 968: Final CASP11 Target Ts812: Sparse Data Contacts
Status: Closed
Created: 08/12/2014
Points: 100
Expired: 08/17/2014 - 16:00
Difficulty: Intermediate
Description: For our last CASP11 puzzle, the CASP organizers have provided "sparse" experimental data about possible contacts in the protein. Contacts are scored with the Contact Map filter in this puzzle, and there is an upper limit of 7225 possible points from the filter. Secondary structure predictions from the SAM server have been delayed, but PSIPRED predictions are provided in the starting structure.
Categories: CASP11, Overall, Predicted Contacts, Prediction

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Comments

spmm's picture
User offline. Last seen 41 weeks 2 days ago. Offline
Joined: 08/05/2010
Groups: Void Crushers
698 closed a year ago
beta_helix's picture
User offline. Last seen 5 days 19 hours ago. Offline
Joined: 05/09/2008
Groups: None
typo fixed

:-)

bkoep's picture
User offline. Last seen 16 hours 10 min ago. Offline
Joined: 11/15/2012
Groups: None
Deadline amended

The expiration date for this puzzle has been reduced by one day in accordance with the CASP target deadline.

Joined: 07/21/2013
Groups: Beta Folders
Is this the last CASP puzzle?

Is this the last CASP puzzle?

beta_helix's picture
User offline. Last seen 5 days 19 hours ago. Offline
Joined: 05/09/2008
Groups: None
Yes, this is the last CASP11 puzzle!

The title and description have been updated.
(We were waiting on the final CASP11 target that was released today... but it's too big for Foldit)

wisky's picture
User offline. Last seen 9 weeks 1 day ago. Offline
Joined: 07/13/2011
Extra puzzles

Just my opinion, but I don't feel that any more puzzles should be released until ALL the CASP puzzles are finished.

Just my $.02

beta_helix's picture
User offline. Last seen 5 days 19 hours ago. Offline
Joined: 05/09/2008
Groups: None
but as the final CASP puzzles start to close

we'd eventually only be left with 2 active puzzles (967 & 968).
Also, the final 4 CASP11 puzzles are all Contact Puzzles, and we try to provide some variety with our active puzzles.
969 isn't due until the 21st, so that gives you over 4 days to work on it if you decide not to start it until the last CASP puzzle closes.

Susume's picture
User offline. Last seen 1 week 5 days ago. Offline
Joined: 10/02/2011
Both sets of contacts?

Have you included both Ts812 and Tc812 contacts in this puzzle?

bkoep's picture
User offline. Last seen 16 hours 10 min ago. Offline
Joined: 11/15/2012
Groups: None
Yes

We've included both the Ts812 and Tc812 contacts in this puzzle.

We didn't run a puzzle for the Tc812 contacts alone because we didn't think they provided enough information to be helpful.

Joined: 06/06/2013
Groups: Gargleblasters
final casp

I know that Fold-it can't set deadlines for CASP. There was so little time on this puzzle that I used a sub-optimal structure to start, and never used any end game scripts since the mid-game ones were still gaining points. (Sorry Madde -- that is why I could blow by this morning on points). It is hard for me to see how this scramble would be useful to CASP, science or anything else. I would like to have been able to work the puzzle right.
Perhaps when I have played longer, I might be able to work a puzzle the right way faster. But this struck me as a mad scramble for points even when I felt it was not a "good" solution. I don't feel like my solution did anything except boost team standings. While that might be fun, I'd like it to be something more.
Skippy

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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