908: 70 Residue Monomer Design: Weak Helices
|Name:||908: 70 Residue Monomer Design: Weak Helices|
|Expired:||06/11/2014 - 23:00|
|Description:||This is a design puzzle with 70 residues. Similarly to Puzzle 898b, helices will not score as well as they normally do, and this time we've tweaked the Fragment filter to be less stringent. There are 3 filters enabled on this puzzle: the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well; the Core Existence filter checks that at least 25% of the residues are buried in the core of your design; and the Fragment filter scans for parts of your design that are unlikely to fold up naturally. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!|
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