Here is the sequence logo predicted by the SAM server (NOTE that the numbering is off, because the organizers trimmed off the first 25 residues for this refinement target, so ignore those helical predictions at the start!):
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
Note that these secondary structure predictions are not necessarily present in the model that has been provided in the puzzle.
If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- structure and rebuild,
- control over clashing.