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882: Revisiting Puzzle 124: PDZ Domain
Status: Closed

Summary

Name: 882: Revisiting Puzzle 124: PDZ Domain
Status: Closed
Created: 04/23/2014
Points: 100
Expired: 05/01/2014 - 23:00
Difficulty: Intermediate
Description: This is a throwback puzzle to the early days of Foldit. This domain is a component of many proteins involved in cell signaling. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been. Players will NOT be able to load in any previous solutions for these puzzles.
Categories: Overall, Prediction

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1Go Science9,329100
2Anthropic Dreams9,22283
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Comments

bkoep's picture
User offline. Last seen 36 min 58 sec ago. Offline
Joined: 11/15/2012
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864
_____________________________
If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit:

- try all puzzles not only "beginner" ones,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing

before starting this puzzle.
_____________________________
Original Puzzle:
http://fold.it/portal/node/928207

bkoep's picture
User offline. Last seen 36 min 58 sec ago. Offline
Joined: 11/15/2012
Groups: None
Extended deadline

Due to recent connectivity problems, we are extending the expiration dates on some puzzles. This puzzle will now close May 1, 2014.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons