puzzle picture
863: Abeta Peptide
Status: Closed

Summary

Name: 863: Abeta Peptide
Status: Closed
Created: 03/21/2014
Points: 100
Expired: 03/27/2014 - 23:00
Difficulty: Intermediate
Description: This short peptide is a fragment of a larger protein found in the membrane of neurons. The Abeta peptide is a product of natural proteolysis reactions in brain tissue, but accumulation of this peptide has been linked to Alzheimer's disease. Abeta is very flexible in solution and is known to sample both alpha-helix and beta-sheet conformations, though little else is known about the full range of structures adopted by Abeta. Help us find the highest-scoring structure(s) of this protein!
Categories: Overall, Prediction

Top Groups

RankGroupScorePoints
1Anthropic Dreams8,725100
2Beta Folders8,67686
3Contenders8,61774
4Void Crushers8,61463
5Go Science8,61253

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons