puzzle picture
860: 72 Residue Monomer Design
Status: Closed


Name: 860: 72 Residue Monomer Design
Status: Closed
Created: 03/14/2014
Points: 100
Expired: 03/21/2014 - 23:00
Difficulty: Intermediate
Description: This is a single-chain design puzzle with 72 residues. This puzzle is similar to Puzzle 854, with a few key changes: the Core Exists filter requirement has been relaxed and may allow more "adventuresome" designs; in addition, the Fragment Filter has been omitted, although it may return in a followup refinement round. As usual, the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!
Categories: Design, Overall

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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