puzzle picture
860: 72 Residue Monomer Design
Status: Closed

Summary

Name: 860: 72 Residue Monomer Design
Status: Closed
Created: 03/14/2014
Points: 100
Expired: 03/21/2014 - 23:00
Difficulty: Intermediate
Description: This is a single-chain design puzzle with 72 residues. This puzzle is similar to Puzzle 854, with a few key changes: the Core Exists filter requirement has been relaxed and may allow more "adventuresome" designs; in addition, the Fragment Filter has been omitted, although it may return in a followup refinement round. As usual, the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!
Categories: Design, Overall

Top Groups

RankGroupScorePoints
1Anthropic Dreams10,081100
2Beta Folders10,04484
3Russian team10,01170
4Void Crushers9,99458
5Go Science9,97648

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons