bkoep's picture
User offline. Last seen 11 hours 39 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Glutamates at residues 27 & 28 are predicted to be in a helix. However, the Glutamates at residues 159 & 161 are predicted to be part of a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

________________

If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

Joined: 02/08/2012
Groups: None
More Time

For such a large puzzle it would seem we would have longer to work on it. Maybe 6 day.

bkoep's picture
User offline. Last seen 11 hours 39 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Extended round 2

When Puzzle 823 closes, we'll post a follow-up puzzle for this CASP ROLL target with server predictions. We can extend the deadline for the follow-up puzzle if you would like.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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