815: Revisiting Puzzle 87: Zinc Binding Protein

Summary

Name:

Status:

Closed

Created:

11/27/2013

Points:

100

Expired:

12/04/2013 - 23:00

Difficulty:

Intermediate

Description:

This is a throwback puzzle to the early days of Foldit. A type of metal binding protein. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been. Players will NOT be able to load in any previous solutions for these puzzles.

Categories:

Overall, Prediction

Rank

Group

Score

Points

Anthropic Dreams

8,828

100

Go Science

8,816

L'Alliance Francophone

8,795

Contenders

8,790

Clear the Way

8,784

Rank

Player

Group

Score

Points

gmn 76 1327

Anthropic Dreams

8,822

100

8,815

8,815

8,814

8,812

Rank

Player

Group

Score

Points

karstenw 76 1327

Anthropic Dreams

8,828

100

8,816

8,795

8,794

christioanchauvin 58 29

L'Alliance Francophone

8,792

Wed, 11/27/2013 - 22:36

tjbertram 76 1327

Offline

Joined: 09/25/2012

Groups: None

START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864
_____________________________
If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit:

- try all puzzles not only "beginner" ones,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing

before starting this puzzle.
_____________________________
Original Puzzle:
http://fold.it/portal/node/451446

Fri, 11/29/2013 - 20:43

brow42 76 351

Offline

Joined: 09/19/2011

Groups: None

Overwhelmed by possibilities

This is a pretty fascinating puzzle. It wasn't long before I had a fairly natural looking fold that ALSO had a tight symmetric cluster of 4 cysteines and 2 histidines. I'm not sure how to distribute my bridges, or how many bridges I should have. As my score increased, things started to wander apart. Any suggestions for how the active site should look?