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814: Ferredoxin Pentamer Design: Round 2
Status: Closed


Name: 814: Ferredoxin Pentamer Design: Round 2
Status: Closed
Created: 11/22/2013
Points: 100
Expired: 12/03/2013 - 23:00
Difficulty: Intermediate
Description: This is a repost of Puzzle 805, with a few important changes. First of all, this puzzle is debuting the new Fragment Filter and Remix Tool to help you design proteins that are likely to fold up in the lab. The protein backbone is no longer frozen, but there is an RMSD condition on most of the residues, to maintain the ferredoxin-like fold. This protein chain includes an extra helix at the N- or C-terminus, although you can redesign it to whatever shape you likeā€”this helix is ignored by the RMSD condition. Reset the puzzle to alternate between the extended N- and C-terminus versions. This puzzle also includes a Residue IE filter, which monitors that all PHE, TYR, and TRP residues are scoring well.
Categories: Design, Overall, Symmetry

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Joined: 06/24/2008
Groups: Void Crushers

Is there the 50 point bonus on this puzzle for getting rid of the low scoring side chains?

beta_helix's picture
User offline. Last seen 2 weeks 5 days ago. Offline
Joined: 05/09/2008
Groups: None
No Bonus

That bonus has been turned off.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons