puzzle picture
Beginner Puzzle (<150): Docking Design
Status: Closed

Summary

Name: Beginner Puzzle (<150): Docking Design
Status: Closed
Created: 09/12/2013
Points: 100
Expired: 10/24/2013 - 23:00
Difficulty: Beginner
Description: We are giving you a helix positioned over a hydrophobic groove where binding occurs in nature. You can mutate any residue on the helix but none on the native binding region. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. For players with fewer than 150 global points.

START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864
_____________________________

If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit :
- try all puzzles not only "Beginners" ones,
- fold first the ones you like the most,
- try it by yourself to understand what works and what doesn't,
- ask for tips in global chat when you think you don't understand something.

Make sure you have followed these tutorials:
- Lonely Sheets,
- Lock and Lower,
- Rebuild,
- Structure and Rebuild,
- Movin' Along,
- Control over Clashing,
- Intro to Design,
- Swappin' Sidechains,
- Mass Mutate,
- Insertion and Deletion

before starting this puzzle.

Categories: Beginner

Top Groups

RankGroupScorePoints
1Team Hungary10,719100
2Anthropic Dreams10,71286
3Go Science10,69774
4Czech National Team10,68763
5Beta Folders10,66153

Top Evolvers

RankPlayerGroupScorePoints
1Shadee 82 1780 Repro-men10,605100

Top Soloists

RankPlayerGroupScorePoints
1gurra66 82 1780  10,741100
2histon 82 1780 Hun-Magyar Csapat10,719100
3Punzie 82 1780  10,716100
4Biochemica 82 274  10,71599
5MrBrown77 82 1780  10,71499


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Comments

marie_s's picture
User offline. Last seen 2 years 2 weeks ago. Offline
Joined: 05/18/2008
Groups: None
If red lines appears

the little part is too far away.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons