775: Player-Solution Redesign: Negative Design
|Name:||775: Player-Solution Redesign: Negative Design|
|Expired:||09/13/2013 - 16:00|
|Description:||In this puzzle you can redesign a player solution from Puzzle 742. The starting structure is the monomer subunit for a top-scoring solution by Galaxie, jamiexq, and tokens. See if you can find a higher-scoring sequence that stabilizes the design fold! This puzzle has an RMSD condition, so don't stray too far from the starting fold. We've also included alignments to two decoy folds—alternative high-scoring folds for the same amino acid sequence. New designs that also destabilize the decoy folds will be prime candidates for synthesis in the Baker lab! See the puzzle comments for more details.|
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