Switching between accurate wiggle and imprecise wiggle blows up protein. Sometimes causes crash.

Case number:699969-995640
Opened by:MattTheGeek
Opened on:Tuesday, July 30, 2013 - 09:13
Last modified:Thursday, August 1, 2013 - 22:30

No, it's not a simple blow up that occurs when you have a unstable fold.

Quickly double (or triple, or even quadruple) clicking the wiggle mode, while wiggling causes this. Spaghetti anyone?

Normal blow ups do occur on stable proteins when slowly switching wiggle modes.

It tends to occur when clashing importance is set less than one.

Clicking show isosurface when the protein is in this (Spaghetti) state causes a crash.

Repeatedly clicking on use less precise wiggle causes the game to crash. see "log_clicking_mode"

You can even still work with the protein. Normalize corrects the protein structure to (almost) normal.

OS: Windows 7 (x86)
Processor: AMD Athlon 64 X2 3800+ Windsor
RAM: 2048MB DDR2 (667Mhz)
Graphics: Nvidia GeForce 6150SE

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log_clicking_mode.txt49.07 KB
log_show_isosurface.txt17.99 KB
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(Tue, 07/30/2013 - 09:13  |  6 comments)

Susume's picture
User offline. Last seen 18 hours 16 min ago. Offline
Joined: 10/02/2011

I have also seen this; checking "use less precise wiggle" during a wiggle explodes the (otherwise very stable) protein. This has happened several times at CI less than 1; I have not tried it at full CI.

Joined: 11/05/2010
Groups: None

I have seen this only once on my several clients and that one quickly re-stabilized with no apparent harm. All my clients using less precise wiggle. It surprised me too, and I thought I might be heading down a path that the protein might not recover from, but in my one case, it worked out just fine.. No similar circumstance has happened since then which was 2nd night after devprev update that allowed the less precise wiggle..

Joined: 11/05/2010
Groups: None

I should add, I only saw it the one time ' because ' I had the protein in view. If the protein had not been in view, I would not have seen it at all. Since 90+% of my proteins are out of view for faster processing, this video artifact ( which is what I consider it to be ) may have occurred hundreds of times without my seeing it. Obviously it has had no detrimental effect on me, else I would be saying something about it.

Joined: 09/20/2011
Groups: Marvin's bunch

it did a fantastic job of blowing uo one of mine - shame it didn't have lights on

spmm's picture
User offline. Last seen 1 week 1 day ago. Offline
Joined: 08/05/2010
Groups: Void Crushers

It happened to me once when I changed it during a wiggle all - now I take care to wait for a shake before I change wiggle state which works fine, can't see any point in clicking repeated between the two states and expecting it to remain stable. Enough things to break already :D

katfish's picture
User offline. Last seen 5 years 50 weeks ago. Offline
Joined: 01/09/2013

Thanks for the reports, everyone. This is something we're aware of and working to fix. Hang in there!


Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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