puzzle picture
734: Player-Solution Loop Redesign
Status: Closed


Name: 734: Player-Solution Loop Redesign
Status: Closed
Created: 06/20/2013
Points: 100
Expired: 06/24/2013 - 23:59
Difficulty: Intermediate
Description: This is a puzzle where you can redesign part of a player-designed protein. Galaxie's top-scoring solution from Puzzle 720 shows promise in the Baker Lab's folding simulations, but one loop seems to be a little troublesome. Help us redesign this loop to find a solution that will fold up properly! You can insert up to four residues and mutate residues near the loop, but most of the protein is frozen in this puzzle.
Categories: Design, Overall

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons