718: Hand-Folding Flu Puzzle: Design the Core
|Name:||718: Hand-Folding Flu Puzzle: Design the Core|
|Expired:||05/30/2013 - 19:00|
|Description:||In this puzzle we are trying to create a new better core for one of the Baker Lab flu proteins. We know what the key interface residues should be, that's why you can't change them, but a new core may increase the stability of the protein. Ultimately a more stable protein might translate into a better protein therapeutic. We don't want you to drift too far from the initial topology, so this puzzle has an RMSD condition. You might want to mutate the core of the protein before you wiggle to not violate this condition. Because this is a Hand-Folding round, only GUI scripts are allowed and sharing has been disabled. More details about all this in the puzzle comments.|
|Categories:||Design, Hand-Folding, Overall|
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