puzzle picture
Beginner Puzzle (<15): Killer Toxin
Status: Closed

Summary

Name: Beginner Puzzle (<15): Killer Toxin
Status: Closed
Created: 05/20/2013
Points: 100
Expired: 06/20/2013 - 23:00
Difficulty: Beginner
Description: Ustilago maydis is a fungal pathogen of maize, some strains of which secrete killer toxins. This is a short 79-residue protein for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold. For players with fewer than 15 global points.
Categories: Beginner

Top Groups

Top Soloists

RankPlayerGroupScorePoints
1Bobnine 79 1470  9,744100
2Ilya Petrovich 79 1470  9,72999
3Carl Kenner 79 1470  9,68898
4NewSodEnt 79 1470  9,66497
5dimension9 79 1470 Anthropic Dreams9,61496


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Comments

Joined: 09/25/2012
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

_____________________________

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :
- try all puzzles not only "beginners" one,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
- ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- quest to the native
- control over clashing
before starting this puzzle.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons