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712: 5-year-anniversary puzzle: 2010
Status: Closed

Summary

Name: 712: 5-year-anniversary puzzle: 2010
Status: Closed
Created: 05/07/2013
Points: 100
Expired: 05/21/2013 - 03:00
Difficulty: Intermediate
Description: Puzzle "Unsolved monkey virus protein" is from the third year of Foldit, as we look back at the last 5 years. Of course we had to pick this puzzle when looking back at 2010! We are giving you these 10 incorrect NMR models to work on. Every time you reset the puzzle it will cycle through these 10 structures and they are available in the Alignment Tool so you can use partial threading between them. You can read all about why this Foldit puzzle was so important in the puzzle comments.
Categories: Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 11 hours 45 min ago. Offline
Joined: 05/09/2008
Groups: None
Here is a link to the now famous puzzle, from 2010:

http://fold.it/portal/node/989012

Note how many player comments that Unsolved monkey virus protein puzzle generated at the time!

My favorite comment is of course this one from spvincent:
http://fold.it/portal/node/989012#comment-9808

...since it turned out to be spvincent's beautiful Foldit prediction that was the first step in solving the crystal structure! :-)

If you want to read the Nature Structural & Molecular Biology paper, you can download at the bottom of this Baker Lab webpage:
http://depts.washington.edu/bakerpg/drupal/node/435

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons