puzzle picture
706: De-novo Freestyle 23 Round 2
Status: Closed


Name: 706: De-novo Freestyle 23 Round 2
Status: Closed
Created: 04/24/2013
Points: 100
Expired: 05/03/2013 - 13:00
Difficulty: Intermediate
Description: This is Round 2 for Puzzle 703. You will be able to load in your manual saves from 703 and use them as a starting point here. This puzzle has been opened up to allow for sharing and the use of all scripts. See if you can improve your model from the first round using these tools! Unlike Puzzle 703, the secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.
Categories: Overall, Prediction

Top Groups

1Beta Folders10,917100
2Anthropic Dreams10,89783
4Clear the Way10,85455
5Go Science10,85344

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Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 11, 47, 72 & 93 are highly predicted to be part of a helix. However, the Valines at residues 103 & 117 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons