puzzle picture
698 (<150): Human cancer protein interaction network target
Status: Closed

Summary

Name: 698 (<150): Human cancer protein interaction network target
Status: Closed
Created: 04/05/2013
Points: 100
Expired: 04/17/2013 - 08:00
Difficulty: Beginner
Description: The solution structure of this dead ringer-like protein has already been solved using NMR, but the crystal structure has yet to be released. We are giving you all 20 models from the NMR ensemble. Every time you reset the puzzle it will cycle through these 20 structures and they are available in the Alignment Tool so you can use partial threading between them. We look forward to seeing how close to the crystal structure you are able to get! For players with fewer than 150 global points.
Categories: Overall, Prediction

Top Groups

RankGroupScorePoints
1Mojo Risin'11,178100
2NessunDorma11,13168
3L'Alliance Francophone11,08944
4Anthropic Dreams11,07727
5E?????! Heureka!11,07116

Top Soloists

RankPlayerGroupScorePoints
1shawn42 83 1969  11,372100
2lizzieD 83 1969  11,31496
3fordesk 83 1969  11,29691
4GhychCtyq 83 1969  11,25387
5Tlaloc 83 276 Mojo Risin'11,17883


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Comments

beta_helix's picture
User offline. Last seen 9 hours 16 min ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

Additional information on partial threading here:
http://fold.it/portal/node/989193#comment-9965
_____________________________

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :
- try all puzzles not only "beginners" one,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
- ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing
before starting this puzzle.

marie_s's picture
User offline. Last seen 1 year 4 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is an alignment puzzle

So make sure you have also followed the tutorials:
- basic threading
- alignin sequence

you can also see on the wiki these pages :
http://foldit.wikia.com/wiki/The_Alignment_Tool
http://foldit.wikia.com/wiki/Alignment_Tool

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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