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698: Human cancer protein interaction network target
Status: Closed

Summary

Name: 698: Human cancer protein interaction network target
Status: Closed
Created: 04/05/2013
Points: 100
Expired: 04/17/2013 - 08:00
Difficulty: Beginner
Description: The solution structure of this dead ringer-like protein has already been solved using NMR, but the crystal structure has yet to be released. We are giving you all 20 models from the NMR ensemble. Every time you reset the puzzle it will cycle through these 20 structures and they are available in the Alignment Tool so you can use partial threading between them. We look forward to seeing how close to the crystal structure you are able to get!
Categories: Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 3 days 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
Please make sure to try out all 20 starting NMR models

Additional information on partial threading here:
http://fold.it/portal/node/989193#comment-9965

Link to PDB entry of NMR ensemble:
http://www.rcsb.org/pdb/explore/explore.do?structureId=2kk0

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons