puzzle picture
689b: Hand-Folding CASP10 T0711 Repost
Status: Closed

Summary

Name: 689b: Hand-Folding CASP10 T0711 Repost
Status: Closed
Created: 03/20/2013
Points: 100
Expired: 03/28/2013 - 11:00
Difficulty: Intermediate
Description: We are reposting this 33 residue CASP10 target to try out the new Disulfide Count Score Filter. Only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. We are again giving you the top-predicted templates from 3 different alignment programs. More details about this CASP target are in the puzzle comments.
Categories: CASP10, Hand-Folding, Overall, Prediction

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Comments

Joined: 05/09/2008
Groups: None
Additional info about this puzzle:

This puzzle uses the new Disulfide Count Score Filter to address some of the problems pointed out by players when this puzzle was posted during CASP10:
http://fold.it/portal/node/992993#comment-18429
____________________________________________________

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=120
____________________________________________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

You can see that these secondary structure predictions imply that this protein is mostly loop!
____________________________________________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=1lu0
http://www.pdb.org/pdb/explore/explore.do?structureId=1w7z
http://www.pdb.org/pdb/explore/explore.do?structureId=1h9h

____________________________________________________

For those of you who miss your scripts, don't worry: the "normal" version of this puzzle will be reposted next week (allowing you to you to load in your manual saves from this puzzle).

Joined: 05/09/2008
Groups: None
This is the reposted version of 689

because I noticed that 689: Hand-Folding CASP10 T0711 Repost
http://fold.it/portal/node/994778
did not have the new Disulfide Count Score Filter on!
Sorry about that!

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