687: 76 Residue Monomer Repost
|Name:||687: 76 Residue Monomer Repost|
|Expired:||03/21/2013 - 01:00|
|Description:||We are giving you a single chain of 76 residues to design. You will need the latest version of the client to play this puzzle There are 4 filters enabled in this puzzle. They are slow to compute, so you may want to check "Disable slow filters" in the behavior tab for when you are manually pulling and running your scripts. The ResidueIE filter ensures PHY, TYR, and TRP residues are scoring well. The "Core Exists" filter ensures the number of residues in the core is between 30% and 70%. The "Polar Core" filter that the residues in the core are properly hydrophobic. The "Layer Design" filter looks at the interactions of the residues based on the surface area of the protein. Residues can be either in the core, on the boundary or on the surface of the protein. Depending on the surroundings, the "Layer Design" filter will give you a bonus if your amino acid matches what it was expecting. Press TAB on each residue to find out more about these filters. You will not be able to load in your solutions from 676. Because of issues with the filters in that puzzle, we wanted to get a fresh start with these new filters. If everything goes well, nearing the end of this puzzle we will post a 76 residue symmetric dimer puzzle where you will be able to load your solution from this monomer into the dimer. Keep that in mind when you are designing your monomer.|
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