puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
226Roman Estep 113 2760  8,7051
227maxodon 113 2760  8,7001
228alvaro100 113 2760  8,6811
229lacie 113 2760  8,6801
230ibertrunkly 113 2760  8,6671
231AIDA64 113 2760  8,6671
232InbredScorpion 113 2760  8,6631
233alodos 113 2760  8,6571
234Sci1217 113 2760  8,6371
235NAHA3 113 2760  8,6051
236Demented Lord 113 2760  8,6001
237blend 113 2760  8,5971
238jaysmasher 113 2760  8,5861
239dart193 113 2760  8,5691
240cherry39 113 2760  8,5491
241matteoT 113 2760  8,5401
242crawlee34225 113 2760  8,5281
243pmoulthrop 113 2760  8,5281
244martinf 113 1286  8,4971
245WDDial 113 2760  8,4761
246theamazingkarl 113 2760  8,4621
247jbhrp3 113 2760  8,4501
248Arzul 113 2760  8,4471
249bruxb 113 2760  8,4351
250cyberjax 113 2760  8,4281


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Comments

Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons