puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
226Roman Estep 78 1584  8,7051
227maxodon 78 1584  8,7001
228alvaro100 78 1584  8,6811
229lacie 78 1584  8,6801
230ibertrunkly 78 1584  8,6671
231AIDA64 78 1584  8,6671
232InbredScorpion 78 1584  8,6631
233alodos 78 1584  8,6571
234Sci1217 78 1584  8,6371
235NAHA3 78 1584  8,6051
236Demented Lord 78 1584  8,6001
237blend 78 1584  8,5971
238jaysmasher 78 1584  8,5861
239dart193 78 1584  8,5691
240cherry39 78 1584  8,5491
241matteoT 78 1584  8,5401
242crawlee34225 78 1584  8,5281
243pmoulthrop 78 1584  8,5281
244martinf 78 466  8,4971
245WDDial 78 1584  8,4761
246theamazingkarl 78 1584  8,4621
247jbhrp3 78 1584  8,4501
248Arzul 78 1584  8,4471
249bruxb 78 1584  8,4351
250cyberjax 78 1584  8,4281


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Comments

beta_helix's picture
User offline. Last seen 4 days 14 hours ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

marie_s's picture
User offline. Last seen 1 year 50 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

beta_helix's picture
User offline. Last seen 4 days 14 hours ago. Offline
Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons