puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
176noops1 79 1450  9,0863
177jtollenaar 79 1450  9,0853
178nemo7731 79 1450  9,0823
179jogie62 79 1450  9,0643
180anne romaine 79 1450  9,0613
181Bithalbierer 79 1450 Team Schleswig-Holstein9,0613
182anna_k1729 79 1450  9,0563
183Schnecke 79 1450  9,0313
184BigMusel 79 1450  9,0262
185krakkdawgg 79 1450  9,0182
186Crossed Sticks 79 279  9,0092
187kdieber 79 1450  9,0022
188ask80 79 1450  8,9892
189syoifczeri 79 1450  8,9852
190yitzy 79 1450  8,9772
191Arne Heessels 79 176  8,9732
192Mox1 79 1450  8,9712
193aendgraend 79 1450 SETI.Germany8,9582
194atimeswift 79 1450  8,9532
195regman7 79 1450  8,9522
196GRandall64 79 1450  8,9462
197AleXusher 79 1450  8,9302
198wisky 79 233 8,9272
199ds_36 79 1450  8,9242
200rinze 79 111  8,9172


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Comments

beta_helix's picture
User offline. Last seen 21 hours 38 min ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

marie_s's picture
User offline. Last seen 1 year 45 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

beta_helix's picture
User offline. Last seen 21 hours 38 min ago. Offline
Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons