puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
176noops1 78 1936  9,0863
177jtollenaar 78 1936  9,0853
178nemo7731 78 1936  9,0823
179jogie62 78 1936  9,0643
180anne romaine 78 1936  9,0613
181Bithalbierer 78 1936 Team Schleswig-Holstein9,0613
182anna_k1729 78 1936  9,0563
183Schnecke 78 1936  9,0313
184BigMusel 78 1936  9,0262
185krakkdawgg 78 1936  9,0182
186Crossed Sticks 78 94  9,0092
187kdieber 78 1936  9,0022
188ask80 78 1936  8,9892
189syoifczeri 78 1936  8,9852
190yitzy 78 1936  8,9772
191Arne Heessels 78 225  8,9732
192Mox1 78 1936  8,9712
193aendgraend 78 940 SETI.Germany8,9582
194atimeswift 78 1936  8,9532
195regman7 78 1936  8,9522
196GRandall64 78 1936  8,9462
197AleXusher 78 1936  8,9302
198wisky 78 1936 8,9272
199ds_36 78 1936  8,9242
200rinze 78 110  8,9172


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Comments

Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

marie_s's picture
User offline. Last seen 1 year 9 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons