puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
151Captain Kirk 71 1514  9,2426
152wosser1 71 1514  9,2366
153twisted1 71 1514  9,2366
154YGK 71 1514  9,2255
155Petrifolder 71 1514  9,2225
156ncm25_OLD 71 1514  9,2185
157shankwiler 71 1514  9,2095
158hippichic 71 1514  9,2015
159matosfran 71 1514  9,2005
160dbuske 71 1514 Gargleblasters9,1985
161boondog 71 1514  9,1794
162spocksbrain 71 1514  9,1714
163oroko 71 1514  9,1694
164aacates 71 1514  9,1684
165DrMistry 71 1514  9,1634
166otong1 71 1514 L'Alliance Francophone9,1574
167frisno 71 1514  9,1504
168SouperGenious 71 1514  9,1394
169callmeAKA 71 1514  9,1364
170monkry 71 1514  9,1354
171Blipperman 71 138  9,1053
172parsnip 71 130  9,1013
173ManVsYard 18 127 Gargleblasters9,0993
174Thrianya 71 1514  9,0943
175lamoille 71 1514 Anthropic Dreams9,0943


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Comments

beta_helix's picture
User offline. Last seen 49 min 42 sec ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

marie_s's picture
User offline. Last seen 1 year 23 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

beta_helix's picture
User offline. Last seen 49 min 42 sec ago. Offline
Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons