puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
151Captain Kirk 78 1451  9,2426
152wosser1 78 1451  9,2366
153twisted1 78 1451  9,2366
154YGK 78 1451  9,2255
155Petrifolder 78 1451  9,2225
156ncm25iori 78 1451  9,2185
157shankwiler 78 1451  9,2095
158hippichic 78 1451  9,2015
159matosfran 73 141  9,2005
160dbuske 29 257 Gargleblasters9,1985
161boondog 78 369  9,1794
162spocksbrain 78 1451  9,1714
163oroko 78 1451  9,1694
164aacates 78 1451  9,1684
165DrMistry 78 1451  9,1634
166otong1 78 820 L'Alliance Francophone9,1574
167frisno 78 1451  9,1504
168SouperGenious 78 1451  9,1394
169callmeAKA 78 1451  9,1364
170monkry 78 1451  9,1354
171Blipperman 15 36  9,1053
172parsnip 78 103  9,1013
173ManVsYard 8 106 Gargleblasters9,0993
174Thrianya 78 1451  9,0943
175lamoille 14 375 Anthropic Dreams9,0943


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Comments

beta_helix's picture
User offline. Last seen 1 hour 8 min ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

marie_s's picture
User offline. Last seen 1 year 45 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

beta_helix's picture
User offline. Last seen 1 hour 8 min ago. Offline
Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons