puzzle picture
686: De-novo Freestyle 21
Status: Closed

Soloists

RankPlayerGroupScorePoints
301Michael Comalli 71 1541  7,1571
302Nymphette 71 1541  7,1531
303AndrewGo 71 1541 Cedarburg H.S.7,1361
304hbergal 71 1541  7,1241
305gbdj 71 1541  7,1231
30642416839 71 1541  7,1051
307Vicky_Tsirkone 71 1541  7,0941
308xx--ZERO--xx 71 1541  7,0901
309SpitfireMkIX 71 1541  7,0881
310thelizardking 71 1541  7,0881
311ratmaztek 71 1541  7,0851
312mrbrilla 71 1541  7,0781
313RyanWard 71 1541  7,0781
314WeiKA 71 1541  7,0771
315aspadistra 71 1541 DSN @ Home7,0771
316spjt 71 1541  7,0761
317Andrea Cutuli 71 1541  7,0761
318zotc44 71 1541  7,0761
319mkchoi212 71 1541  7,0761
320spooler 71 1541  7,0761
321 katfish 71 1541  7,0751
322Don Kihot 71 1541  7,0751
323dgrechka 71 1541  7,0751
324test_account1 71 536 test_group17,0751
325vertex 71 1541 Contenders7,0751


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Comments

beta_helix's picture
User offline. Last seen 1 day 18 hours ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

marie_s's picture
User offline. Last seen 1 year 24 weeks ago. Offline
Joined: 05/18/2008
Groups: None
this puzzle is not difficult

It is easiest that many new ones with layers.
Please put this type of puzzle in intermediate, I think new ones may have fun plying with them.

For new ones, just check you have do all these tutorials:
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- control over clashing.

beta_helix's picture
User offline. Last seen 1 day 18 hours ago. Offline
Joined: 05/09/2008
Groups: None
Thanks marie_s

I have switched it to "Intermediate" and we'll make the Design puzzles with Filters "Advanced" from now on (until we are able to make them easier!)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons