puzzle picture
Beginner Puzzle (<150): Streptococcal Protein
Status: Closed


1Wilm 81 1638  9,566100
2Goldschmidt 81 1638  9,55899
3anthion 81 81  9,55198
4soaddict 81 1638  9,53897
5perrya 81 354  9,53796
6Lecc 81 1638 Russian team9,51695
7eromana 81 1638  9,50094
8frisno 81 1638  9,49392
9Part1Zan 81 1638 Russian team9,48791
10Izaak 81 1638  9,48290
11Wguy23 81 1638  9,48189
12AleXusher 81 1638  9,48088
13DWL0 81 1638  9,47187
14Kryzz42z 81 1638  9,45686
15pedrito rod 81 1638  9,45185
16NJL1 81 1638  9,44984
17stv139 81 1638  9,43583
18Farpanda 81 1638  9,42682
19nastik 81 1638  9,42381
20alanrichard 81 1638  9,42080
21tjommis91 81 1638  9,42079
22Adam Streck 81 1638  9,41778
23thelizardking 81 1638  9,41377
24hada 81 584  9,41376
25ekoo1203 81 1638  9,41275

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tamirh's picture
User offline. Last seen 5 years 49 weeks ago. Offline
Joined: 05/11/2012

If you are new to Foldit, here are detailed instructions to get you started:

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

marie_s's picture
User offline. Last seen 1 year 29 weeks ago. Offline
Joined: 05/18/2008
Groups: None
Tlaloc strategy is one between many

and a very old one.

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :

- try all puzzles not only "beginners" one,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
- ask for tips in global when you think you doesn't understand something.

Make sure you have follow the tutorials :
- lonely sheets,
- lock and lower,
- rebuild,
- structure and rebuild,
- quest to the native
- control over clashing
before starting the puzzle.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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