puzzle picture
Beginner Puzzle (<150): Potato Multicystatin
Status: Closed


Name: Beginner Puzzle (<150): Potato Multicystatin
Status: Closed
Created: 01/23/2013
Points: 100
Expired: 02/24/2013 - 12:00
Difficulty: Beginner
Description: We would like to welcome all the new Foldit players that have recently joined us. This puzzle is for you to try out once you've completed the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold. Good luck and welcome to Foldit! For players with fewer than 150 global points.
Categories: Beginner

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Joined: 09/25/2012
Groups: None

If you are new to Foldit, here are detailed instructions to get you started:

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

marie_s's picture
User offline. Last seen 1 year 41 weeks ago. Offline
Joined: 05/18/2008
Groups: None
tlaloc strategy is just one between many

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :

- try all puzzles not only "beginners" one,
- fold first the ones you like the most,
- try by yourself to understand what works and what doesn't,
- make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
- ask for tips in global when you think you doesn't understand something.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons