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664 (<150): Unlocked Frizzled Design Puzzle
Status: Closed

Summary

Name: 664 (<150): Unlocked Frizzled Design Puzzle
Status: Closed
Created: 12/29/2012
Points: 100
Expired: 01/09/2013 - 11:00
Difficulty: Beginner
Description: This is a the same protein as Puzzle 640 (Frizzled with a wider pocket than Puzzle 659) but this time the helix is unlocked. You can mutate any residue on the helix but none on Frizzled. We still have the new "Residue Interaction Energy" filter. Natural proteins avoid putting Tryptophan, Phenylalanine, and Tyrosine on the surface. However, Foldit often gives a score bonus if you load up the surface of your design with Tryptophan. The ResidueIE filter helps to counteract that, helping you make more useful designs. More details in the puzzle comments. For players with fewer than 150 global points.
Categories: Beginner

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RankGroupScorePoints
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2Russian team10,19679
3Piratenpartei Deutschland10,19661
4SETIKAH@KOREA10,18847
5Go Science10,18835

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Comments

beta_helix's picture
User offline. Last seen 6 days 19 hours ago. Offline
Joined: 05/09/2008
Groups: None
Check out the blogpost

for more information about this puzzle:
http://fold.it/portal/node/993721

___________________________________

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

Slow m's picture
User offline. Last seen 6 years 41 weeks ago. Offline
Joined: 01/03/2013
Groups: None
How do I actually start this

How do I actually start this game?

beta_helix's picture
User offline. Last seen 6 days 19 hours ago. Offline
Joined: 05/09/2008
Groups: None
read the post just above yours!
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons