puzzle picture
663: Blind Electron Density 5
Status: Closed

Summary

Name: 663: Blind Electron Density 5
Status: Closed
Created: 12/19/2012
Points: 100
Expired: 01/06/2013 - 14:00
Difficulty: Advanced
Description: This is our fifth electron density puzzle with real data. Unlike the previous puzzles, there are bits of density which don't belong to the copy of the protein that you're working on. However, the protein you're working on should fit entirely within the density box. You'll have to decide which bits of density to match with, and which bits to ignore. Try to fit the protein into the density to get the best score! Secondary Structure Predictions are posted in the puzzle comments.
Categories: Electron Density, Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 21 hours 9 min ago. Offline
Joined: 05/09/2008
Groups: None
Secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 80 is highly predicted to be part of a sheet. However, the Isoleucines at residues 12 & 44 have an equal probability of being anything.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons