puzzle picture
659 (<150): Re-Return of the Tissue Regeneration Design Puzzle
Status: Closed


Name: 659 (<150): Re-Return of the Tissue Regeneration Design Puzzle
Status: Closed
Created: 12/04/2012
Points: 100
Expired: 12/15/2012 - 23:00
Difficulty: Intermediate
Description: We are giving you a 10 residue helix positioned over a hydrophobic groove where binding occurs in nature. This native binding region in marked by unfrozen side chains. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. If you are new to Foldit, make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4 before trying this puzzle. More details in the puzzle comments. For players with fewer than 150 global points.
Categories: Beginner

Top Groups

1Void Crushers9,242100
3Go Science9,23433
4Piratenpartei Deutschland9,23417

Top Soloists

1cassandraberry81897 83 2324  9,281100
2TheRuralsCalahorra 83 2324  9,27695
3cinny 83 2324  9,26890
4creinholt 83 2324  9,25184
5Rhyslarn 83 2324 Void Crushers9,24280

Need this puzzle? Log in to download.  


tamirh's picture
User offline. Last seen 7 years 48 weeks ago. Offline
Joined: 05/11/2012
More info here:

This is a repost of Puzzle 571: Tissue Regeneration Design Puzzle, but with a new filter that should help with the scoring artifacts that were prevalent in that puzzle. We tried this with puzzle 633 but the ResidueIE filter was broken and this caused windows machines to crash. With the ResidueIE filter fixed, we wanted to try the puzzle again.

More background on this puzzle can be found in the original blogpost: http://fold.it/portal/node/992888

User login
Download links:
  Windows    OSX    Linux  
(10.12 or later)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media

Only search fold.it
Other Games: Mozak
Recommend Foldit
Top New Users

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons