Wed, 11/14/2012 - 18:23
#2
I *hope* this is CASP Roll 0025
Since R0023 is due on the 16th?
Wed, 11/14/2012 - 21:53
#3
Nice catch
Thanks auntdeen, indeed this is R0025 (and the links in the first comment are all correct)
Fri, 11/16/2012 - 03:22
#4
how do u play
how the heck do u play the game?
Fri, 11/16/2012 - 03:24
#5
START HERE:
just press the button:
"Click here to start playing"
that is above the list of puzzles:
http://fold.it/portal/puzzles
Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casproll/target.cgi?id=69
You'll notice that the sequence we have given you has been trimmed (compared to the one on the CASP ROLL website). This is because the N-terminus is predicted to be a signal peptide by the Rosetta Server:
http://rosettaserver.bakerlab.org/results.jsp?id=34809
For more info on that: http://en.wikipedia.org/wiki/Signal_peptide
____________________________________________________
Here is the sequence logo predicted by the SAM server.
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Valine at residue 104 is highly predicted to be part of a loop. However, the Valine at residue 47 is not predicted to be anything!
The above predictions are already on the starting model (based on the horizontal lines in the above figure).
____________________________________________________
Link to template PDBs:
http://www.pdb.org/pdb/explore/explore.do?structureId=1sr3 http://www.pdb.org/pdb/explore/explore.do?structureId=4ex5 http://www.pdb.org/pdb/explore/explore.do?structureId=1qzg