puzzle picture
Beginner Puzzle: Headpiece Domain of Chicken Villin
Status: Closed

Summary

Name: Beginner Puzzle: Headpiece Domain of Chicken Villin
Status: Closed
Created: 10/29/2012
Points: 100
Expired: 12/01/2012 - 23:00
Difficulty: Beginner
Description: This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is stuck in a local minimum, can you use the Foldit tools you just learned to improve the model and match the guide?
Categories: Overall

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Comments

Joined: 12/06/2008
Groups: Contenders
Headless Chicken Villain returns!

Aaaaaack. The puzzle from my nightmares has returned.

Joined: 06/25/2011
Groups: Texas Fold'em
re: Headless Chicken Villain returns!

Muahahahahaha! This puzzle should be easy.

beta_helix's picture
User offline. Last seen 23 hours 26 min ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

Get Started: Download
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons