beta_helix's picture
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Additional info about this CASP Roll target

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casproll/target.cgi?id=64

You'll notice that the sequence we have given you has been trimmed (compared to the one on the CASP ROLL website). This is because the N-terminus is predicted to be a signal peptide by the Rosetta Server:
http://rosettaserver.bakerlab.org/results.jsp?id=34067

For more info on that: http://en.wikipedia.org/wiki/Signal_peptide
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Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 1, 42 & 83 are highly predicted to be part of a sheet. However, the Valines at residues 9, 10 & 100 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
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Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3dxe http://www.pdb.org/pdb/explore/explore.do?structureId=2jgb http://www.pdb.org/pdb/explore/explore.do?structureId=3na2

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