puzzle picture
637: De-novo Freestyle 16
Status: Closed

Summary

Name: 637: De-novo Freestyle 16
Status: Closed
Created: 10/04/2012
Points: 100
Expired: 10/10/2012 - 23:59
Difficulty: Advanced
Description: This currently unsolved short protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments.
Categories: Overall, Prediction

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1Anthropic Dreams9,831100
2Void Crushers9,76583
3foldeRNA9,73569
4Contenders9,71356
5Beta Folders9,67445

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Comments

beta_helix's picture
User offline. Last seen 2 days 3 hours ago. Offline
Joined: 05/09/2008
Groups: None
Here are the secondary structure predictions!

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 20 & 45 are highly predicted to be part of a sheet. However, the Valine at residue 2 is not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

spmm's picture
User offline. Last seen 36 weeks 5 days ago. Offline
Joined: 08/05/2010
Groups: Void Crushers
pivots

this has a pivot around 36-43

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons