puzzle picture
Beginner Puzzle: Streptococcal Protein
Status: Closed

Summary

Name: Beginner Puzzle: Streptococcal Protein
Status: Closed
Created: 08/20/2012
Points: 100
Expired: 09/28/2012 - 23:00
Difficulty: Beginner
Description: The fold of this Streptococcal Protein is trapped in a local minimum. Although it looks good, it is incorrect. This is a short 57-residue protein for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold.
Categories: Overall

Top Groups

RankGroupScorePoints
31Team Norway9,2512
32SETIKAH@KOREA9,2371
33Atlanta9,1411
34Ukraine9,1171
35machinelves9,1101

Top Evolvers

RankPlayerGroupScorePoints
31AsDawnBreaks 75 1437 Beta Folders9,44282
32aendgraend 75 1437 SETI.Germany9,28581

Top Soloists

RankPlayerGroupScorePoints
31jakbinimbol 75 1437  9,56282
32truestone 75 1437 Gargleblasters9,56181
33tokens 75 1437 Anthropic Dreams9,55880
34phallicies 75 1437  9,55880
35brow42 75 1437  9,55879


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Comments

beta_helix's picture
User offline. Last seen 38 min 6 sec ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons