puzzle picture
615: CASP10 Refinement Puzzle: TR754
Status: Closed


Name: 615: CASP10 Refinement Puzzle: TR754
Status: Closed
Created: 08/06/2012
Points: 100
Expired: 08/14/2012 - 23:59
Difficulty: Beginner
Description: This is the twenty-fourth and final CASP10 Refinement Target. This model was the best server prediction for target T0754, generated by the Zhang Server. We've been told that ~77% of this model matches the native, so you'll need to refine ~23% of the structure. Luckily, this target only has 68 residues. More info in the puzzle comments.
Categories: CASP10, Overall, Prediction

Top Groups

1Anthropic Dreams9,462100
3Beta Folders9,37362
5putting the eat in meat9,34237

Top Evolvers

Top Soloists

Need this puzzle? Log in to download.  


beta_helix's picture
User offline. Last seen 5 hours 35 min ago. Offline
Joined: 05/09/2008
Groups: None
More info here:

This is the page for this CASP10 refinement target:

Note that the organizers gave us this hint:

"Starting model's GDT_TS=77."

GDT_TS=77 essentially means that ONLY 77% of the model superimposes correctly onto the native structure:

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 58 is highly predicted to be part of a helix. However, the Valine at residue 2 is predicted to be in a sheet.

User login
Download links:
  Windows    OSX    Linux  
(10.12 or later)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media

Only search fold.it
Other Games: Mozak
Recommend Foldit
Top New Users

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons