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610: CASP10 Refinement Puzzle: TR750
Status: Closed

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beta_helix's picture
User offline. Last seen 13 hours 2 min ago. Offline
Joined: 05/09/2008
Groups: None
More info here:

Please note that the Cut Tool is available on all puzzles from now on!

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=202

The CASP10 organizers gave us this hint:

"Starting model GDT_TS=77."

GDT_TS=77 essentially means that 77% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 84 & 176 are highly predicted to be part of a helix. However, the Valines at residues 64-65 & 99 are predicted to be part of a sheet.

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