puzzle picture
601: CASP10 Refinement Puzzle: TR723
Status: Closed


Name: 601: CASP10 Refinement Puzzle: TR723
Status: Closed
Created: 07/14/2012
Points: 100
Expired: 07/28/2012 - 23:00
Difficulty: Beginner
Description: This is the twelfth CASP10 Refinement Target. This model was the best server prediction for target T0723, generated by the Matrix server. We've been told that ~85% of this model matches the native, so you just need to find which 15% to refine! More info in the puzzle comments.
Categories: CASP10, Overall, Prediction

Top Groups

3Anthropic Dreams11,20466
5Beta Folders11,16742

Top Evolvers

Top Soloists

Need this puzzle? Log in to download.  


beta_helix's picture
User offline. Last seen 2 weeks 5 days ago. Offline
Joined: 05/09/2008
Groups: None
More info here:

This is the page for this CASP10 refinement target:

Note that the organizers gave us this hint:

"Starting model GDT_TS=85."

GDT_TS=85 essentially means that 85% of the model superimposes correctly onto the native structure:

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 42, 67, 86, 99, 103 & 122 are highly predicted to be part of a helix. However, the Valines at residues 17 & 94 are predicted to be anything.

User login
Download links:
  Windows    OSX    Linux  
(10.12 or later)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media

Only search fold.it
Other Games: Mozak
Recommend Foldit
Top New Users

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons