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590: CASP10 Target T0728
Status: Closed

Summary

Name: 590: CASP10 Target T0728
Status: Closed
Created: 07/03/2012
Points: 100
Expired: 07/13/2012 - 05:00
Difficulty: Intermediate
Description: The twelfth CASP10 target is another tough one, as it's 154 residues. We are providing you with 4 different templates, but all of them have a similar topology (that we hope is the correct one!). We will provide you with server predictions soon. More details about this CASP target are in the puzzle comments.
Categories: CASP10, Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 4 days 8 hours ago. Offline
Joined: 05/09/2008
Groups: None
Additional info about this CASP target

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=148
____________________________________________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 8, & 17 are highly predicted to be in a helix. However, the Leucine at residue 60 is predicted to be in a sheet.
____________________________________________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3d33
http://www.pdb.org/pdb/explore/explore.do?structureId=2eig
http://www.pdb.org/pdb/explore/explore.do?structureId=3jqw
http://www.pdb.org/pdb/explore/explore.do?structureId=2l3b

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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