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582: Beginner CASP10 Refinement Puzzle: TR674
Status: Closed

Groups

RankGroupScorePoints
1Go Science11,627100
2L'Alliance Francophone11,59679
3Contenders11,55562
4Anthropic Dreams11,55248
5foldeRNA11,54137
6Team China11,50728
7Team Hungary11,46421
8FoldIt@Netherlands11,46216
9Void Crushers11,40112
10putting the eat in meat11,3969
11Russian team11,3236
12Androids11,3225
13Gargleblasters11,2983
14xkcd11,2222
15Another Hour Another Point11,2192
16Richard Dawkins Foundation11,2181
17Mojo Risin'11,1801
187Monkeys11,1621
19Freedom Folders11,1181
20E?????! Heureka!11,0401
21SETI.Germany10,9871
22Natural Abilities10,8971
23Nerdfighters10,8261
24Czech National Team10,7941
25Newton's Cradle10,7941


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beta_helix's picture
User offline. Last seen 1 day 4 hours ago. Offline
Joined: 05/09/2008
Groups: None
More info here:

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=131&view=refinement

Note that the organizers gave us this hint:

"Starting model GDT_TS=84."

GDT_TS=84 essentially means that 84% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test

Secondary Structure Predictions below:

beta_helix's picture
User offline. Last seen 1 day 4 hours ago. Offline
Joined: 05/09/2008
Groups: None
Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 10, 12 & 45 are highly predicted to be part of a helix. However, the Valine at residue 93 is predicted to be in a sheet.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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