puzzle picture
582: Beginner CASP10 Refinement Puzzle: TR674
Status: Closed

Summary

Name: 582: Beginner CASP10 Refinement Puzzle: TR674
Status: Closed
Created: 06/21/2012
Points: 100
Expired: 06/30/2012 - 02:00
Difficulty: Beginner
Description: This is the sixth CASP10 Refinement Target. This model was the best human prediction for target T0674. We've been told that ~84% of this model matches the native, so you just need to find which 16% to refine! More info in the puzzle comments.
Categories: CASP10, Overall, Prediction

Top Groups

RankGroupScorePoints
1Go Science11,627100
2L'Alliance Francophone11,59679
3Contenders11,55562
4Anthropic Dreams11,55248
5foldeRNA11,54137

Top Evolvers

Top Soloists



Need this puzzle? Log in to download.  

Comments

beta_helix's picture
User offline. Last seen 1 day 15 hours ago. Offline
Joined: 05/09/2008
Groups: None
More info here:

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=131&view=refinement

Note that the organizers gave us this hint:

"Starting model GDT_TS=84."

GDT_TS=84 essentially means that 84% of the model superimposes correctly onto the native structure:
http://en.wikipedia.org/wiki/Global_distance_test

Secondary Structure Predictions below:

beta_helix's picture
User offline. Last seen 1 day 15 hours ago. Offline
Joined: 05/09/2008
Groups: None
Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 10, 12 & 45 are highly predicted to be part of a helix. However, the Valine at residue 93 is predicted to be in a sheet.

Get Started: Download
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.7 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Search
Only search fold.it
Recommend Foldit
User login
Soloists
Evolvers
Groups
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons