Here is the CASP link for this Refinement target:
Here is the sequence logo predicted by the SAM server.
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
For example, the Leucines at residues 87 & 110-11 are highly predicted to be in a sheet. However, the Leucine at residue 20 is predicted to be anything.
Note that we are giving you over 7 days to work on this one.
It's a large protein you have 3 templates to work with, so we hope that you will try changing the alignments on each of them.
I hope you enjoy the structure of this protein.
I just wanted to add that like Puzzle 576, the starting model is not the one CASP gave us (which was another RosettaServer model). We have given you the closest non-Rosetta server model (it's only 1.12 Angstroms RMSD away from the model chosen by the CASP organizers) so that you will be able to find high-scoring solutions that are slightly different than the ~78% correct starting structure.
You can read more about the motivation for this here:
indeed very very very cool!