puzzle picture
578: Beginner Flu Puzzle 4
Status: Closed

Summary

Name: 578: Beginner Flu Puzzle 4
Status: Closed
Created: 06/14/2012
Points: 100
Expired: 06/25/2012 - 10:00
Difficulty: Beginner
Description: We are looking for the best locations to place & design FIVE linked residues on the surface of Influenza H3 Hemagglutinin. We have placed 2 helices on either side so that it will be easier to build scaffolds for your designs. Mutate the 5 sidechains while looking for good hydrophobic pockets or residues to make strong hydrogen bonds to. If you are new to Foldit, make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4 before trying this puzzle.
Categories: Design, Overall

Top Groups

RankGroupScorePoints
1Contenders9,138100
2Go Science9,13777
3foldeRNA9,13659
4Anthropic Dreams9,12744
5Team Hungary9,11433

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Comments

beta_helix's picture
User offline. Last seen 9 hours 1 min ago. Offline
Joined: 05/09/2008
Groups: None
Please read the blogpost about this puzzle:

http://fold.it/portal/node/992977

NOTE: This puzzle is up for over 9 days due to the particularly heavily load of CASP10 puzzles this week.

Joined: 12/01/2011
Groups: Go Science
Error message

I am getting an error message when i try to open 578
"Unrecognized setup options specified: replonly"
Win 7 - 64

dsn's picture
User offline. Last seen 7 years 22 weeks ago. Offline
Joined: 09/24/2011
Groups: None
Error message

I am also getting an error message as shown above "Unrecognized setup options...", when trying to open 578.

Joined: 09/20/2011
Groups: None
Ditto on the error... :(

Ditto on the error... :(

brow42's picture
User offline. Last seen 1 week 5 days ago. Offline
Joined: 09/19/2011
Groups: None
Error

This puzzle can only be played in the developer preview. Instructions for switching to dev prev are in the FAQ. However, this puzzle being posted means that either the main client is going to get an update Real Soon, or this puzzle is going to get cancelled (again.)

beta_helix's picture
User offline. Last seen 9 hours 1 min ago. Offline
Joined: 05/09/2008
Groups: None
I am very sorry about this

This was my mistake, the new update resolves this:
http://fold.it/portal/node/992983

I have extended the puzzle deadline by a few hours to make up for this.
My apologies again and thank you for your patience!

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons